Weight Loss Shots: Full-Dose GLP-1, Explained

Prescription medication. Medical evaluation required. Pricing is for a monthly supply.

A weight loss shot is a once-weekly injection that works with your body's own appetite and metabolism hormones to reduce hunger and support steady, sustainable weight loss. At Fitish RX, weight loss shots are full-dose compounded GLP-1 medications, semaglutide and tirzepatide, prescribed through provider-led telehealth and shipped to your door. No clinic visits, no insurance runaround, transparent all-in pricing.

What is a weight loss shot?

"Weight loss shot" is the everyday name for a GLP-1 injection. GLP-1 medications mimic a hormone your body already makes that signals fullness, slows how quickly the stomach empties, and helps regulate blood sugar. The result for most people is less hunger, fewer cravings, and a more consistent path toward their goal weight when paired with reasonable nutrition and movement. These are prescription medications, so a licensed provider reviews your health history before one is prescribed.

The two main weight loss shots: semaglutide and tirzepatide

Fitish RX offers both of the leading GLP-1 options:

• Compounded semaglutide ($219 / monthly supply). A GLP-1 receptor agonist and one of the most widely studied weight management medications. A foundational, once-weekly option.
• Compounded tirzepatide ($339 / monthly supply). A dual-action GLP-1 and GIP medication. By working on two appetite and metabolism pathways at once, it tends to deliver steadier appetite control for many patients.

Both are once-weekly subcutaneous injections, gradually titrated by your provider. Not sure which fits you? Complete your intake and a provider will recommend the right one.

How weight loss shots work

GLP-1 (and, in tirzepatide, GIP) are hormones involved in appetite, digestion, and blood sugar. A weekly weight loss shot extends and amplifies those signals, so you feel full sooner, stay full longer, and experience less of the "food noise" that drives reactive eating. Your provider starts you at a low dose and steps it up gradually over the first weeks and months, which gives your body time to adjust and keeps side effects manageable.

Full dose or microdose

Fitish RX offers two distinct lanes so you can match the program to your goal:

• Full-dose weight loss shots. Compounded semaglutide and tirzepatide at standard weight-management dosing, for patients who meet clinical criteria and want meaningful weight loss.
• Microdosing. A lower, fixed dose for those who want a gentle, mindful, cosmetic approach rather than full-dose weight loss. It does not titrate up.

What to expect

Most patients begin to notice appetite changes within the first 1 to 2 weeks, with visible weight changes typically following over 8 to 16 weeks of consistent use alongside hydration, protein, and movement. The most common side effects are mild to moderate and tend to ease as your body adjusts: nausea, reduced appetite, fatigue, and digestive changes such as constipation. Starting low and increasing slowly is the best way to stay comfortable. Your provider reviews the full safety profile with you, and you can message your care team through the patient portal at no added cost.

Who qualifies

Weight loss shots are prescribed for adults whose BMI and medical history meet clinical eligibility criteria, as determined by a licensed provider. They are not right for everyone, and your provider will tell you if another path fits you better.

How to get a weight loss shot online with Fitish RX

Getting started takes minutes. You complete a short online intake about your health and goals. A licensed provider reviews it, and if a GLP-1 is appropriate, writes your prescription. Your medication ships discreetly from a licensed compounding pharmacy on a monthly cadence, and your care team stays with you through the patient portal for dose adjustments and questions. Learn more about getting a GLP-1 online prescription or browse all weight loss treatments.

Frequently asked questions

What is the best weight loss shot?

There is no single best option for everyone. Semaglutide is the most widely studied GLP-1, while tirzepatide is dual-action and tends to deliver steadier appetite control for many patients. A licensed provider recommends the right one based on your health profile and goals.

How much do weight loss shots cost at Fitish?

Compounded semaglutide is $219 and compounded tirzepatide is $339 for a monthly supply. Each price includes your provider consult, the medication if approved, and shipping. There are no separate consult or membership fees.

Can I get weight loss shots online?

Yes. Fitish RX is provider-led telehealth. You complete an online intake, a licensed provider reviews it, and approved prescriptions ship to your door monthly.

Do I need insurance?

No. Fitish RX is direct-pay with transparent, all-in pricing.

Are weight loss shots safe?

GLP-1 medications are prescription treatments with a well-documented safety profile, and most side effects are mild and temporary. They are only prescribed after a licensed provider reviews your health history, and your care team supports you throughout.

Compounded medications are prepared by a state licensed pharmacy. Compounded medications are not FDA-approved and do not undergo FDA review for safety, effectiveness, or manufacturing quality. FDA-approved GLP-1 products are commercially available, and your provider may recommend a compounded option where clinically appropriate based on your evaluation.

These statements have not been evaluated by the Food and Drug Administration. Individual results vary. This product is not intended to diagnose, treat, cure, or prevent any disease. For more detail, see The Clinic FAQ page or our Fitish RX Safety Information.